A Study in Healthy Male Subjects to Understand How Savolitinib When Taken With Midazolam Behaves Inside the Body

PHASE1CompletedINTERVENTIONAL
Enrollment

14

Participants

Timeline

Start Date

December 27, 2019

Primary Completion Date

March 6, 2020

Study Completion Date

March 6, 2020

Conditions
Solid Tumors
Interventions
DRUG

Savolitinib

Single dose (together with midazolam) on Study Day 5 after a high fat, high calorie breakfast.

DRUG

Midazolam

Single dose (alone) on Study Day 1 and single dose (together with savolitinib) on Study Day 5, both after a high fat, high calorie breakfast.

Trial Locations (1)

21225

Research Site, Baltimore

Sponsors

Lead Sponsor

Collaborators (1)

All Listed Sponsors
collaborator

Parexel

INDUSTRY

lead

AstraZeneca

INDUSTRY