Weight Loss Impact on Male Fertility

NACompletedINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

January 10, 2019

Primary Completion Date

August 20, 2020

Study Completion Date

January 22, 2023

Conditions
ObesitySub Fertility, MaleMetabolic Syndrome
Interventions
DIETARY_SUPPLEMENT

Very Low Carb Ketogenic Diet

Patients will be submitted to very low-calorie ketogenic dietary intervention (VLCK) according to the recommendations of the Pronokal® Method program including lifestyle and physical activity guidelines. The ketogenic stage (phase 1-3) consists of a VLCD diet (600-800 kcal / d), with low carbohydrate intake and lipids. The amount of high biological value proteins ranges from 0.8 to 1.2 g / kg of body weight / day. This first stage (ketogenic) is maintained until the patient reaches the goal of reducing the target weight by 80% to be reduced, being variable in time, according to the response of each patient. After this period, it evolved to a non-ketogenic stage, initiating the hypocaloric diet (800 to 1500 Kcal), with progressive introduction of other food groups, reducing weight more slowly. The maintenance stage consists of a balanced diet, ranging from 1500 to 2000 Kcal.

Trial Locations (1)

05403000

Hospital das Clinicas da Faculdade de Medicina da USP, São Paulo

All Listed Sponsors
lead

University of Sao Paulo

OTHER

NCT04186767 - Weight Loss Impact on Male Fertility | Biotech Hunter | Biotech Hunter