Impact of the Transpulmonary Pressure on Right Ventricle Function in Acute Respiratory Distress Syndrome

NACompletedINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

June 11, 2020

Primary Completion Date

June 11, 2022

Study Completion Date

June 11, 2022

Conditions
Acute Respiratory Distress Syndrome
Interventions
OTHER

Pneumotachograph

"Measurements will be performed during the first three days of Acute Respiratory Distress Syndrome management :~* The first measurement will be performed 5 minutes after the initial ventilator settings.~* Measurements will be repeated systematically at 24 hours, 48 hours and 72 hours of evolution.~* An additional measure will be performed at each positive end-expiratory pressure modification (maximum 5 measures)."

OTHER

Esophageal catheter

"Measurements will be performed during the first three days of Acute Respiratory Distress Syndrome management~* The first measurement will be performed 5 minutes after the initial ventilator settings.~* Measurements will be repeated systematically at 24 hours, 48 hours and 72 hours of evolution.~* An additional measure will be performed at each positive end-expiratory pressure modification (maximum 5 measures)."

OTHER

Transthoracic and / or transesophageal cardiac ultrasound

"The right ventricle systolic function will be assessed thanks to a transthoracic cardiac ultrasound in children, and a transthoracic of a transesophageal cardiac ultrasound in adults :~Measurements will be performed during the first three days of Acute Respiratory Distress Syndrome management :~* The first measurement will be performed 5 minutes after the initial ventilator settings.~* Measurements will be repeated systematically at 24 hours, 48 hours and 72 hours of evolution.~* An additional measure will be performed at each positive end-expiratory pressure modification (maximum 5 measures)."

OTHER

Electrical impedance tomography (EIT) for pediatric patients

For pediatric patients: measurements will be performed during the first three days of Acute Respiratory Distress Syndrome management.

Trial Locations (2)

75015

Hôpital Necker-Enfants Malades, Paris

92100

Hôpital Ambroise Paré, Boulogne-Billancourt

All Listed Sponsors
collaborator

URC-CIC Paris Descartes Necker Cochin

OTHER

lead

Assistance Publique - Hôpitaux de Paris

OTHER

NCT04184674 - Impact of the Transpulmonary Pressure on Right Ventricle Function in Acute Respiratory Distress Syndrome | Biotech Hunter | Biotech Hunter