Metformin as Add-on to the Standard Therapy in Patients With Chronic Hepatitis B

NACompletedINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

March 13, 2020

Primary Completion Date

July 2, 2021

Study Completion Date

September 13, 2021

Conditions
Chronic Hepatitis B
Interventions
DRUG

Metformin & Entecavir

Adding sustained-release metformin hydrochloride (1000 mg, oral, once a day) for 24 weeks to the ongoing entecavir therapy (0.5 mg, oral, once a day)

DRUG

Placebo & Entecavir

Adding placebo (oral, once a day) for 24 weeks to the ongoing entecavir therapy (0.5 mg, oral, once a day)

Trial Locations (1)

271000

The 960th Hospital of Chinese PLA Joint Logistics Support Force (Jinan Military General Hospital), Tai’an

All Listed Sponsors
collaborator

Jinan Military General Hospital

OTHER

lead

Fu-Sheng Wang

OTHER

NCT04182321 - Metformin as Add-on to the Standard Therapy in Patients With Chronic Hepatitis B | Biotech Hunter | Biotech Hunter