Adaptive Interventions for Optimizing Malaria Control: a Cluster-Randomized SMART Trial

NACompletedINTERVENTIONAL
Enrollment

122,872

Participants

Timeline

Start Date

December 1, 2019

Primary Completion Date

August 31, 2024

Study Completion Date

August 31, 2024

Conditions
LLIN, PBO LLIN, IRS, Larviciding
Interventions
OTHER

Regular long-lasting insecticidal nets

Olyset nets: containing 2% permethrin or PermaNet 2.0 containing 1.8 and 1.4 g/kg, respectively, for 75 and 100 denier yarn

OTHER

LLIN plus Piperonyl butoxide-treated LLIN

Olyset Plus: containing 2% permethrin and 1% PBO

OTHER

Long-lasting microbial larvicide

Semi-permanent and permanent habitats will be treated with FourStar® 180-day Briquets using the recommended dosage of 100 ft2 water surface per briquet

OTHER

Indoor residual spraying with micro-encapsulated pirimiphos-methyl or other insecticides

Each dwelling's interior walls and ceilings will be sprayed with micro-encapsulated pirimiphos-methyl at the recommended dosage of 1g/m² and at the recommended frequency of once a year or twice a year. Other insecticides may be used to replace the Actellic 300 CS depends on Kenya government policy, current policy requires rotating different insecticides annually.

Trial Locations (2)

92697

Program in Public Health, Irvine

Unknown

Tom-Mboya University College, Maseno University, Homa Bay

All Listed Sponsors
lead

University of California, Irvine

OTHER

NCT04182126 - Adaptive Interventions for Optimizing Malaria Control: a Cluster-Randomized SMART Trial | Biotech Hunter | Biotech Hunter