Low Grade Inflammation in Childhood Obesity : an Independent Risk Factor for Endothelial Dysfunction

NACompletedINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

March 1, 2019

Primary Completion Date

December 31, 2021

Study Completion Date

December 31, 2021

Conditions
Obesity, ChildhoodObesityEndothelial DysfunctionCardiovascular Risk FactorInflammation
Interventions
DIAGNOSTIC_TEST

Anthropometry

"* Actual Height and weight~* Calculated BMI from measured weight and height.~* Pubertal development (Tanner stage)~* Waist circumference~* Skin fold measurement (Triceps and Subscapular)~* Waist-to-height ratio will be calculated from measured height and waist circumference."

DIAGNOSTIC_TEST

Blood pressure

Blood pressure will be measured using an oscillometric, electronic device (Mindray). The blood pressure will be measured 3 times; the first measurement will not be taken into account and the mean of the second and third measurement will be considered as the real blood pressure.

DIAGNOSTIC_TEST

Peripheral arterial tonometry

The investigator will measure the pulse wave amplitude by using a finger plethysmograph (peripheral arterial tonometry). The investigator will use the EndoPAT device from Itamar Medical Ltd. At the end of the examination, the participants will be asked to give a VAS-score (Visual Analogue Pain scale).

OTHER

Questionnaire

General questionnaire on cardiovascular risk factors

DIAGNOSTIC_TEST

Blood sample

Blood sample for hs-CRP

Trial Locations (1)

1090

University Hospital of Brussels, Brussels

All Listed Sponsors
lead

Universitair Ziekenhuis Brussel

OTHER

NCT04181398 - Low Grade Inflammation in Childhood Obesity : an Independent Risk Factor for Endothelial Dysfunction | Biotech Hunter | Biotech Hunter