Effects of Anti-IL5 Biological Treatments on Blood IgE Levels in Severe Asthmatic Patients

CompletedOBSERVATIONAL
Enrollment

130

Participants

Timeline

Start Date

October 11, 2019

Primary Completion Date

October 1, 2020

Study Completion Date

November 1, 2020

Conditions
AsthmaAsthma; Eosinophilic
Interventions
DIAGNOSTIC_TEST

Total IgE

Levels of total IgE before biological treatments and at 4±2 months of treatments

DIAGNOSTIC_TEST

Blood cell counts

White Blood Cell Count and Differential (and in particular the levels of total leucocytes, lymphocytes, eosinophils and basophils)

DIAGNOSTIC_TEST

Asthma control assessment

Levels of asthma control assessed by asthma control questionnaire (ACT) before initiation of biological treatments and at 4± months of treatments

DIAGNOSTIC_TEST

lung function tests

Lung function tests performed before initiation of biological treatments and at 4± months of treatments

Trial Locations (8)

44124

Azienda Ospedaliero Universitaria Ferrara, Ferrara

Unknown

Professor of Respiratory Medicine Department of Medical and Surgical Sciences University of Foggia - Italy, Foggia

UOC Pneumologia Ospedale L.Sacco - Polo Univestiario ASST Fatebenefratelli - Milano, Milan

Malattie dell' Apparato Respiratorio Dipartimento di Scienza Mediche e Chirurgiche Materni-Infantili e dell'Adulto. Azienda Ospedaliero Universitaria di Modena, Modena

AOUP Giaccone Palermo, dipartimento PROMISE, Università di Palermo, Palermo

S.C di Pneumologia Ospedale S. Maria degli Angeli AAS5 Friuli Occidentale, Pordenone

Department of Medical Specialties, Pneumology Unit, Arcispedale Santa Maria Nuova, Azienda USL di Reggio Emilia-IRCCS, Reggio Emilia

UOC Pneumologia Azienda Ospedaliera Univeristaria Integrata - Verona, Verona

All Listed Sponsors
lead

Università degli Studi di Ferrara

OTHER

NCT04181190 - Effects of Anti-IL5 Biological Treatments on Blood IgE Levels in Severe Asthmatic Patients | Biotech Hunter | Biotech Hunter