Impact of Positive Airway Pressure Therapy on Clinical Outcomes in Older Veterans With Chronic Obstructive Pulmonary Disease and Comorbid Obstructive Sleep Apnea (Overlap Syndrome)

NARecruitingINTERVENTIONAL
Enrollment

668

Participants

Timeline

Start Date

December 1, 2020

Primary Completion Date

March 31, 2026

Study Completion Date

December 31, 2026

Conditions
Sleep Apnea SyndromeObstructive Sleep ApneaCOPDOverlap SyndromeQuality of LifeNeurocognitive FunctionSleepinessElderlyPositive Airway Pressure
Interventions
DEVICE

Positive airway pressure

Positive airway pressure therapy. OVS patients randomized to PAP therapy arm will be titrated to optimal PAP therapy per standard protocol and assigned to use PAP therapy.

OTHER

Conservative care (control arm)

Eligible OVS patients will receive conservative care/usual care with education about sleep apnea and sleep hygiene via handouts and video instructions. This is the control arm.

Trial Locations (1)

48201-1916

RECRUITING

John D. Dingell VA Medical Center, Detroit, MI, Detroit

All Listed Sponsors
lead

VA Office of Research and Development

FED