Pharmacokinetics and Hepatic Safety of EGCG

PHASE1CompletedINTERVENTIONAL
Enrollment

39

Participants

Timeline

Start Date

November 24, 2020

Primary Completion Date

January 31, 2022

Study Completion Date

January 31, 2022

Conditions
Uterine Fibroids
Interventions
DIETARY_SUPPLEMENT

Epigallocatechin gallate (EGCG)

800 mg (4 capsules) of EGCG (green tea extract), taken orally on a daily basis for up to 2 months

DRUG

Clomiphene Citrate

100 mg for 5 days

DRUG

Letrozole

5 mg for 5 days

Trial Locations (1)

21205

Johns Hopkins Medicine, Baltimore

All Listed Sponsors
collaborator

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NIH

collaborator

University of Illinois at Chicago

OTHER

collaborator

Johns Hopkins University

OTHER

collaborator

University of Chicago

OTHER

lead

Yale University

OTHER