Prospective Randomized Study of Accelerated Radiation Therapy (PRART)

PHASE3Active, not recruitingINTERVENTIONAL
Enrollment

400

Participants

Timeline

Start Date

November 21, 2019

Primary Completion Date

July 15, 2025

Study Completion Date

June 30, 2030

Conditions
Breast Cancer
Interventions
RADIATION

Radiation therapy - 3 weeks

Patients randomized to ARM 1 will receive whole breast radiotherapy of 4050cGY and a concomitant boost to the tumor bed of 4800cGY in 15 fractions

RADIATION

Radiation therapy - 2 weeks

Patients randomized to ARM 2 will receive whole breast radiotherapy of 3200cGY and a concomitant boost to the tumor bed of 4200cGY in 10 fractions.

Trial Locations (3)

10007

New York Presbyterian Hospital at Lower Manhattan Cancer Center, New York

11215

Brooklyn Methodist Hospital - NewYork Presbyterian, New York

11355

New York Presbyterian Hospital - Queens, New York

All Listed Sponsors
lead

Weill Medical College of Cornell University

OTHER