A Study of ABT-199 (Venetoclax) for Cutaneous T Cell Lymphoma (CTCL)

PHASE1CompletedINTERVENTIONAL
Enrollment

4

Participants

Timeline

Start Date

January 15, 2020

Primary Completion Date

February 10, 2021

Study Completion Date

June 22, 2021

Conditions
CTCL
Interventions
DRUG

ABT-199 (venetoclax)

Eligible patients will be enrolled into the study and receive venetoclax daily per the US FDA package insert guidelines of venetoclax, with dose escalation up to 400 mg. To minimize the risk of tumor lysis syndrome (TLS), and following the package insert directions for dose escalation over 5 weeks, the initial dose is 20 mg daily, and may be progressively increased as tolerated to 400 mg by week 5.

Trial Locations (1)

06520

Yale New Haven Hospital / Smilow Cancer Center, New Haven

All Listed Sponsors
lead

Yale University

OTHER

NCT04171791 - A Study of ABT-199 (Venetoclax) for Cutaneous T Cell Lymphoma (CTCL) | Biotech Hunter | Biotech Hunter