4
Participants
Start Date
January 15, 2020
Primary Completion Date
February 10, 2021
Study Completion Date
June 22, 2021
ABT-199 (venetoclax)
Eligible patients will be enrolled into the study and receive venetoclax daily per the US FDA package insert guidelines of venetoclax, with dose escalation up to 400 mg. To minimize the risk of tumor lysis syndrome (TLS), and following the package insert directions for dose escalation over 5 weeks, the initial dose is 20 mg daily, and may be progressively increased as tolerated to 400 mg by week 5.
Yale New Haven Hospital / Smilow Cancer Center, New Haven
Yale University
OTHER