70
Participants
Start Date
October 29, 2019
Primary Completion Date
April 2, 2022
Study Completion Date
June 28, 2022
Metformin Hydrochloride 850 mg Tablets
Oral administration of Metformin hydrochloride 850 mg tablets (1700 mg/day) daily until the completion of neoadjuvant chemotherapy cycles
AC-T chemotherapy regimen
AC: (Doxorubicin 60 mg/m2 IV + cyclophosphamide 600 mg/m2 IV) for 4 cycles every 3 weeks followed by Taxol cycles (Paclitaxel 80 mg/m2 IV) once weekly for 12 weeks.
Damanhour University, Beheira
Alexandria University
OTHER
Damanhour University
OTHER