Effects of Transcranial Direct Current Stimulation (tDCS) on Language

NACompletedINTERVENTIONAL
Enrollment

25

Participants

Timeline

Start Date

December 13, 2019

Primary Completion Date

July 1, 2024

Study Completion Date

July 1, 2024

Conditions
StrokeAphasia
Interventions
DEVICE

Targeted Transcranial Direct Current Stimulation

High-Definition-tDCS will be delivered via a battery-driven constant direct current stimulator (Soterix) using a 4x1 montage (1 central anodal electrode and 4 cathodal electrodes) arranged in a HD-cap. The current is turned on and increased in a ramplike fashion over approximately 30 seconds until reaching a strength of no more than 2mA, with a current density equal to 0.08mA/cm2. Stimulation will be maintained no longer than 20 minutes, and stimulation will be applied to the targeted region.

DEVICE

Active Control Transcranial Direct Current Stimulation

High-Definition-tDCS will be delivered via a battery-driven constant direct current stimulator (Soterix) using a 4x1 montage (1 central anodal electrode and 4 cathodal electrodes) arranged in a HD-cap. The current is turned on and increased in a ramplike fashion over approximately 30 seconds until reaching a strength of no more than 2mA, with a current density equal to 0.08mA/cm2. Stimulation will be maintained no longer than 20 minutes, and stimulation will be applied to the active control region.

BEHAVIORAL

Phonologic-Focused Speech Therapy

Participants are asked to generate or choose from a list phonologic information about a target picture.

BEHAVIORAL

Semantic-Focused Speech Therapy

Participants who have difficulty retrieving an object name are given hierarchical clues or asked questions about the objects function as a way of activating the semantic network for that object, leading to eventual retrieval of the target word.

Trial Locations (1)

53226

Medical College of Wisconsin, Milwaukee

All Listed Sponsors
lead

Medical College of Wisconsin

OTHER

NCT04166513 - Effects of Transcranial Direct Current Stimulation (tDCS) on Language | Biotech Hunter | Biotech Hunter