Canadian Biomarker Integration Network for Depression (CAN-BIND) - Validation Study

PHASE3CompletedINTERVENTIONAL
Enrollment

1

Participants

Timeline

Start Date

December 23, 2019

Primary Completion Date

December 31, 2022

Study Completion Date

December 31, 2022

Conditions
Major Depressive Disorder
Interventions
DRUG

Escitalopram

Participants are given escitalopram for 8 weeks. At week 8, those classified as responders will continue on escitalopram until the end of study.

DRUG

Brexpiprazole

Participants who are classified as non-responders are given 8 weeks add-on brexpiprazole, in addition to escitalopram, for the remainder of the study.

Trial Locations (6)

T2N 2T9

University of Calgary, Calgary

V6T2A1

University of British Columbia, Vancouver

L8P3B6

McMaster University, Hamilton

K7L4X3

Queen's University, Kingston

M5T2S8

University Health Network, Toronto

M6J1H4

Centre for Addiction and Mental Health, Toronto

All Listed Sponsors
collaborator

Unity Health Toronto

OTHER

collaborator

Baycrest

OTHER

collaborator

Centre for Addiction and Mental Health

OTHER

collaborator

McMaster University

OTHER

collaborator

Queen's University

OTHER

collaborator

University of Ottawa

OTHER

collaborator

University of British Columbia

OTHER

collaborator

University of Calgary

OTHER

collaborator

McGill University

OTHER

collaborator

Dalhousie University

OTHER

collaborator

University of Michigan

OTHER

collaborator

Simon Fraser University

OTHER

lead

University Health Network, Toronto

OTHER

NCT04162522 - Canadian Biomarker Integration Network for Depression (CAN-BIND) - Validation Study | Biotech Hunter | Biotech Hunter