Mackenzie's Mission: The Australian Reproductive Carrier Screening Project

NACompletedINTERVENTIONAL
Enrollment

18,302

Participants

Timeline

Start Date

November 21, 2019

Primary Completion Date

March 31, 2022

Study Completion Date

December 31, 2024

Conditions
X-Linked Genetic DiseasesAutosomal Recessive Disorder
Interventions
OTHER

Reproductive Genetic Carrier Screening

Carrier screening for approximately 1300 genes associated with severe autosomal recessive and X-linked recessive conditions affecting children will be performed on each member of the couple. A combined result will be issued indicating whether the couple has a 'low' or 'increased' risk of having a child with a genetic condition

Trial Locations (24)

2031

Royal Hospital for Women, Sydney

Sydney Children's Hospital, Randwick, Sydney

2050

Royal Prince Alfred Hospital, Sydney

2145

The Children's Hospital at Westmead, Sydney

Westmead Hospital, Sydney

2170

Liverpool Hospital, Liverpool

2298

Hunter Genetics, Newcastle

2340

Tamworth Communith Health Services, Tamworth

2428

Forster Community Health Service, Forster

2430

Taree Community Health Service, Taree

2560

Campbelltown Hospital, Sydney

2650

Wagga Wagga Base Hospital, Wagga Wagga

3052

Victorian Clinical Genetics Services, Melbourne

3076

Northern Hospital, Melbourne

3084

Mercy Hospital for Women, Melbourne

3820

West Gippsland Heath Service (Warragul Hospital), Warragul

4029

Royal Brisbane and Women's Hospital, Brisbane

4870

Cairns Hospital, Cairns

4880

Mareeba Hospital, Mareeba

5006

Women's and Children's Hospital, Adelaide

6008

King Edward Memorial Hospital, Perth

6027

Joondalup Health Campus, Joondalup

7000

Royal Hobart Hospital, Hobart

0810

Royal Darwin Hospital, Darwin

All Listed Sponsors
collaborator

Australian Government Department of Health and Ageing

OTHER_GOV

collaborator

The University of New South Wales

OTHER

collaborator

The University of Western Australia

OTHER

collaborator

Harry Perkins Institute of Medical Research

UNKNOWN

collaborator

University of Sydney

OTHER

collaborator

Macquarie University, Australia

OTHER

collaborator

Griffith University

OTHER

collaborator

Victorian Clinical Genetics Services

UNKNOWN

collaborator

NSW Health Pathology

UNKNOWN

collaborator

PathWest Laboratory Medicine WA

OTHER_GOV

collaborator

King Edward Memorial Hospital

OTHER

collaborator

Royal Brisbane and Women's Hospital

OTHER_GOV

collaborator

Women's and Children's Hospital, Australia

OTHER_GOV

collaborator

Sydney Children's Hospitals Network

OTHER

collaborator

Royal Hobart Hospital

OTHER_GOV

lead

Murdoch Childrens Research Institute

OTHER