A Study of Pembrolizumab in Combination With Cisplatin and Pemetrexed in Advanced Malignant Pleural Mesothelioma (MPM) (MK-3475-A17)

PHASE1CompletedINTERVENTIONAL
Enrollment

19

Participants

Timeline

Start Date

December 9, 2019

Primary Completion Date

September 21, 2022

Study Completion Date

September 21, 2022

Conditions
Mesothelioma
Interventions
DRUG

Pembrolizumab

Participants will receive Pembrolizumab 200 mg IV every 3 weeks (Q3W) until disease progression, or until participant has received 35 administrations of Pembrolizumab (approximately 2 years).

DRUG

Pemetrexed

Participants will receive Pemetrexed 500 mg/m\^2 IV on Day 1 of each cycle up to 4-6 cycles where each cycle = 3 weeks

DRUG

Cisplatin

Participants will receive Cisplatin 75 mg/m\^2 IV on Day 1 of each cycle up to 4-6 cycles where each cycle = 3 weeks

Trial Locations (4)

663-8501

Hyogo College of Medicine Hospital ( Site 0003), Nishinomiya

241-8515

Kanagawa Cancer Center ( Site 0004), Yokohama

702-8055

JOHAS Okayama Rosai Hospital ( Site 0002), Okayama

104-0045

National Cancer Center Hospital ( Site 0001), Tokyo

All Listed Sponsors
lead

Merck Sharp & Dohme LLC

INDUSTRY

NCT04153565 - A Study of Pembrolizumab in Combination With Cisplatin and Pemetrexed in Advanced Malignant Pleural Mesothelioma (MPM) (MK-3475-A17) | Biotech Hunter | Biotech Hunter