Function of the Pigment Epithelium in Patients With Type 1 Neurofibromatosis

CompletedOBSERVATIONAL
Enrollment

30

Participants

Timeline

Start Date

May 11, 2020

Primary Completion Date

July 21, 2020

Study Completion Date

July 21, 2020

Conditions
Neurofibromatosis Type 1
Interventions
OTHER

Electro-oculogram

Electrophysiological recording of changes in electrical potential across the retinal pigmentary epithelium during successive periods of dark and light adaptation, according to ISCEV standards. Results will comprise dark trough value and light/dark (Arden) ratio.

OTHER

Full-field electroretinogram

Electrophysiological recording of retinal function. Results will comprise amplitudes and latencies of each electroretinography response (dark-adapted 0.01, dark-adapted 3.0, dark-adapted 10.0, dark-adapted 3.0 oscillatory potentials, light-adapted 3.0, light-adapted 3.0 flicker).

Trial Locations (1)

75015

Hôpital Necker-Enfants Malades, Paris

All Listed Sponsors
collaborator

URC-CIC Paris Descartes Necker Cochin

OTHER

lead

Assistance Publique - Hôpitaux de Paris

OTHER

NCT04153344 - Function of the Pigment Epithelium in Patients With Type 1 Neurofibromatosis | Biotech Hunter | Biotech Hunter