CMV-TCR-T Cells for CM Virus Infection After HSCT

PHASE1CompletedINTERVENTIONAL
Enrollment

17

Participants

Timeline

Start Date

December 19, 2019

Primary Completion Date

November 15, 2022

Study Completion Date

November 15, 2022

Conditions
CMV Infection or Reactivation After Allogenic HSCT
Interventions
BIOLOGICAL

CMV-TCR-T cells

Patients with CMV emias or CMV disease will be enrolled, and donor derived CMV-TCR-T(HLA-A\*1101\\0201\\2402) cells will be intravenously infused with a escalated dose of 0.1-1×106 CMV-TCR-T cells. The CMV DNA copies and CMV-TCR-T cell proliferation will be monitored in the scheduled time (day 0, day 4, day 7, day 10, day 14,day 28).

Trial Locations (1)

065200

Hebei Yanda Ludaopei Hospital, Sanhe

All Listed Sponsors
collaborator

China Immunotech (Beijing) Biotechnology Co., Ltd.

INDUSTRY

lead

Hebei Yanda Ludaopei Hospital

OTHER

NCT04153279 - CMV-TCR-T Cells for CM Virus Infection After HSCT | Biotech Hunter | Biotech Hunter