Effect of CGF on Frequency of Alveolar Osteitis Following Partially Erupted Mandibular Third Molar Surgery

NACompletedINTERVENTIONAL
Enrollment

70

Participants

Timeline

Start Date

January 2, 2018

Primary Completion Date

July 15, 2018

Study Completion Date

July 30, 2018

Conditions
Alveolar OsteitisImpacted Tooth
Interventions
PROCEDURE

Concentrated Growth Factor (Test group)

The patients' blood was collected in 9 ml glass tubes and immediately centrifuged to prevent coagulation in special centrifuge device. The CGF program was set up as follows: accelerated for 30 seconds so as to reach 2700 rpm, rotated for 2 minutes, then reduced to 2400 rpm, then rotated again for 4 minutes and accelerated to 2700 rpm, rotated for 4 minutes, then accelerated to 3000 rpm for 3 minutes, and decelerated for 36 seconds to stop. The middle layer in the tube was separated by the ''Buffy coat'' containing the CGFs fibrin gel using forceps and scissor. Then, this fibrin gel was inserted in the extraction cavity.

PROCEDURE

Non-Concentrated Growth Factor (Control group)

Third molar extraction was performed under local anesthesia. Following the extraction, the socket was sutured and natural healing process was observed. This side was considered as a control group.

Trial Locations (1)

35050

Ege University, Izmir

All Listed Sponsors
lead

Ege University

OTHER

NCT04151147 - Effect of CGF on Frequency of Alveolar Osteitis Following Partially Erupted Mandibular Third Molar Surgery | Biotech Hunter | Biotech Hunter