Effects of SIMEOX on Flow and Volume in Healthy Subjects and Patients With COPD

SIMEOX is a device generating a succession of gentle depression at the mouth.

A PEP device (Pari-PEP) will be used to provoke a positive expiratory pressure while exhaling, thereby stabilizing the airways during expiration.

A slow vital capacity maneuver will be performed according to the guidelines, from total lung capacity to residual volume