NCT04142437 - Study to Learn More About the Safety and Effectiveness of the Drug VITRAKVI During Routine Use in Patients With TRK Fusion Cancer Which is Locally Advanced or Spread From the Place Where it Started to Other Places in the Body | Biotech Hunter

Enrollment

150

Participants

Timeline

Start Date

April 3, 2020

Primary Completion Date

November 30, 2029

Study Completion Date

March 31, 2030

Conditions

Locally Advanced or Metastatic Solid Tumor Harboring an NTRK Gene Fusion

Interventions

DRUG

larotrectinib(Vitrakvi, BAY2757556)

In the study, patients treated under local standard of care clinical practice; all decisions in terms of diagnostic procedures, treatments, management of the disease, and resource utilization are fully dependent on mutual agreement between the patient and the attending physician, without interference by the study initiator or study protocol

Trial Locations (76)

10065

RECRUITING

Memorial Sloan Kettering Children's Cancer Center, New York

10305

WITHDRAWN

Staten Island Univ. Hospital (Northwell Health), Staten Island

14210

TERMINATED

Great Lakes Cancer Center, Buffalo

15212

TERMINATED

Allegheny Health Network, Pittsburgh

19104

RECRUITING

Children's Hospital of Philadelphia, Philadelphia

WITHDRAWN

University of Pennsylvania (Penn Med), Philadelphia

21201

WITHDRAWN

Univ. of Maryland / Greenebaum Comp. Cancer Ctr., Baltimore

21205

RECRUITING

Johns Hopkins / Sidney Kimmel Cancer Center, Baltimore

21702

TERMINATED

Frederick Health-James M Stockman Cancer Institute, Frederick

26506

RECRUITING

West Virginia University, Morgantown

27834

RECRUITING

East Carolina University / Vidant Health, Greenville

28204

WITHDRAWN

Levine Cancer Center, Charlotte

29425

RECRUITING

Medical Univ. of South Carolina, Charleston

32224

WITHDRAWN

Mayo Clinic, Jacksonville

32827

WITHDRAWN

Nemours Children's Hospital, Orlando

33146

RECRUITING

University of Miami, Miami

33155

RECRUITING

Nicklaus Children's Hospital, Miami

37232

RECRUITING

Vanderbilt University Medical Center, Nashville

38105

WITHDRAWN

St. Jude Children's Research Hospital, Memphis

43210

WITHDRAWN

Ohio State Comp. Cancer Ctr. / James Cancer Hospital, Columbus

44501

RECRUITING

Mercy Health Youngstown, Youngstown

46804

RECRUITING

Fort Wayne Medical Oncology Hematology, Fort Wayne

47802

WITHDRAWN

Regional Health Hope Center, Terre Haute

48334

RECRUITING

Detroit Clinical Research Center, Farmington Hills

48912

RECRUITING

Sparrow Cancer Center, Lansing

53717

TERMINATED

SSM Health Cancer Center - Dean Medical Group, Madison

54601

RECRUITING

Gundersen Health System, La Crosse

67214

RECRUITING

Cancer Center of Kansas, Wichita

75390

RECRUITING

UT Southwestern Medical Center / Children's Health, Dallas

77030

RECRUITING

MD Anderson Cancer Center, Houston

81501

WITHDRAWN

SCL Health, Grand Junction

82663

RECRUITING

Hoag Memorial Hospital Presbyterian, Newport Beach

84107

WITHDRAWN

Intermountain Healthcare - Intermountain Medical Center, Murray

84112

RECRUITING

Univ. of Utah / Huntsman Cancer Center, Salt Lake City

84790

WITHDRAWN

Intermountain Healthcare - Dixie Regional Medical Center, St. George

85202

WITHDRAWN

Banner Desert Medical Center, Mesa

89169

RECRUITING

Nevada Cancer Research Foundation, Las Vegas

90027

RECRUITING

California Research Inst., Los Angeles

90089

WITHDRAWN

USC / Norris Comprehensive Cancer Center, Los Angeles

90095

RECRUITING

UCLA - Mattel Children's Hospital, Los Angeles

90404

TERMINATED

Providence Health System - Southern California, Santa Monica

90502

WITHDRAWN

Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance

94304

RECRUITING

Stanford Univ Med Ctr. / Lucile Packard Children's Hosp, Palo Alto

94609

WITHDRAWN

UCSF Benioff Children's Hospital Oakland, Oakland

98105

RECRUITING

Seattle Children's, Seattle

06520

RECRUITING

Yale University, New Haven

04106

RECRUITING

Maine Health, South Portland

02111

RECRUITING

Tufts / Neely Cancer Center, Boston

02215

WITHDRAWN

Boston Children's / Dana Farber, Boston

07960

WITHDRAWN

Atlantic Hem Onc / Morristown Medical Center, Morristown

08901

WITHDRAWN

Rutgers Cancer Institute of New Jersey, New Brunswick