Exercise and Nutrition on Obese Microbiome

NACompletedINTERVENTIONAL
Enrollment

31

Participants

Timeline

Start Date

October 21, 2019

Primary Completion Date

December 21, 2019

Study Completion Date

December 21, 2019

Conditions
Overweight and Obesity
Interventions
OTHER

Exercise Protocol

The exercise protocol consists of a nine-week progressive intense-conditioning program involving six consecutive days (Monday-Saturday) of one-hour exercises and one-day rest weekly for a total of 54 days of exercise. Exercises are performed in person as a group with other participating subjects and lead by certified instructors. Exercises will involve a variety of activities ranging from running, cycling, whole-body functional movements, power movements, and open-chain weight lifting with barbells and resistance bands.

OTHER

Calorie-Restrictive Low Carbohydrate Diet (CR-LC)

Consists of weekly nutrition plans, counseling and monitoring by on-site registered dietitians and nutritionists for nine weeks. CR-LC consists of caloric and macronutrient restrictions. Caloric restrictions involves a 40% deficit from calculated total daily energy expenditure. Macronutrient restriction involves a high protein, low carbohydrate diet (35% protein, 25% carbohydrate and 40% fat).

OTHER

Ancestral Diet (AD)

Consists of weekly nutrition plans, counseling and monitoring by on-site registered dietitians and nutritionists for nine weeks. AD consists of consuming only whole foods and avoiding processed foods. Emphasis will be on food quality with no caloric or macronutrient restrictions.

Trial Locations (1)

33146

University of Miami, Miami

All Listed Sponsors
lead

University of Miami

OTHER

NCT04138303 - Exercise and Nutrition on Obese Microbiome | Biotech Hunter | Biotech Hunter