Influence of FreeO2 on Percentage of Time Within Oxygen Saturation Target Using Noninvasive Ventilation (NIV) and Continuous Positive Airway Pressure (CPAP) for Patients Admitted for AECOPD or Bariatric Surgery

NARecruitingINTERVENTIONAL
Enrollment

10

Participants

Timeline

Start Date

October 28, 2019

Primary Completion Date

July 31, 2027

Study Completion Date

June 30, 2028

Conditions
COPD ExacerbationOxygen ToxicityAbdominal ObesitySurgery
Interventions
OTHER

Washout period

During this period the patients will breath spontaneously oxygen titrated using the FreeO2 device with a SpO2 target set at 90%. The period duration is 30 minutes.

DEVICE

NIV - FreeO2

"During this period the patients will receive NIV using FreeO2 device for oxygen titration with a SpO2 target set at 90%. Initially, the inspiratory pressure will be set to obtain a tidal volume between 6 to 8 mL/Kg of predictive body weight and positive end-expiratory end pressure (PEEP) at 5 centimeters of water (cmH2O).~After NIV initiation, the parameters can be adjusted to improve patient comfort. The period duration is 30 minutes."

DEVICE

Nasal High flow Oxygen therapy - FreeO2

During this period the patients will receive NHFOT using the FreeO2 device for oxygen titration with a SpO2 target set at 90%. The high flow device will be set at 30 lpm.The period duration is 30 minutes.

OTHER

CPAP - Oxygen constant flow

During this period, the patients will have their own CPAP with oxygen adjusted by hospital staff according to hospital protocol. The period duration is 15 minutes.

OTHER

CPAP - FreeO2

During this period, the patients will have their own CPAP with oxygen adjusted using the FreeO2 device. SpO2 target will be set at 90% The period duration is 60 minutes.

Trial Locations (1)

G1V 4G5

RECRUITING

Institut universitaire de Cardiologie et de Pneumologie - Université Laval, Québec

All Listed Sponsors
lead

François Lellouche

OTHER