Study of PD-1 Inhibitors After CD30.CAR T Cell Therapy in Relapsed/Refractory Hodgkin Lymphoma

EARLY_PHASE1Active, not recruitingINTERVENTIONAL
Enrollment

10

Participants

Timeline

Start Date

September 1, 2019

Primary Completion Date

April 1, 2025

Study Completion Date

July 7, 2037

Conditions
Relapsed Hodgkin LymphomaRefractory Hodgkin Lymphoma
Interventions
BIOLOGICAL

Nivolumab

Nivolumab administered at 240mg every two weeks or 480 mg every four weeks as per standard of care after treatment with CD30.CAR T cells

BIOLOGICAL

Pembrolizumab

Pembrolizumab administered at 200 mg every three weeks or 400 mg every six weeks as per standard of care after treatment with CD30.CAR T cells

Trial Locations (1)

27599

Lineberger Comprehensive Cancer Center at University of North Carolina, Chapel Hill

All Listed Sponsors
collaborator

American Society of Clinical Oncology

OTHER

lead

UNC Lineberger Comprehensive Cancer Center

OTHER