Perioperative Analgesic Efficiency of Quadratus Lumborum Block vs Epidural in Radical Cystectomy

PHASE2CompletedINTERVENTIONAL
Enrollment

34

Participants

Timeline

Start Date

November 15, 2018

Primary Completion Date

September 15, 2020

Study Completion Date

September 15, 2020

Conditions
Pain, Postoperative
Interventions
DRUG

Quadratus Lumborum Block Using Bupivacaine 0.2%

"Ultrasound guided transmuscular approach for quadratus lumborum block using an 18 gauge Touhy's epidural needle to insert the catheter. Normal saline 5 mL will be used to identify that plane. A volume of 20 ml of 0.25% of Bupivacaine bolus will be injected in that plane just over QL. This will be followed by epidural catheter insertion to facilitate continuous infusion. A similar procedure will be performed on the other side. A continuous infusion of 0.2% Bupivacaine at 5 ml/h will be administered to the patient.~This transmuscular quadratus lumborum (TQL) block, has been suggested to be a simple and perhaps safer alternative to the anterior approach as was described for the original QL block"

DRUG

Epidural Analgesia Using Bupivacaine 0.25%

"With Patients placed in sitting position, puncture site will be identified at (T8-9, T9-10, or T10-11) intervertebral spaces. Using aseptic conditions, an 18G Tuohy epidural needle will be used to insert epidural catheter as appropriate.~Induction of epidural analgesia with 10-15 ml bupivacaine 0.25% preoperatively with top up doses of 5-7 ml bupivacaine 0.25% or equivalent administered judiciously till we achieve analgesic level of T4 to L1. The calculated top up doses will be administered each hour using bupivacaine 0.25% or by using a continuous infusion syringe pump for equivalent doses"

Trial Locations (1)

11796

National Cancer Institute - Cairo University, Cairo

All Listed Sponsors
lead

National Cancer Institute, Egypt

OTHER

NCT04133051 - Perioperative Analgesic Efficiency of Quadratus Lumborum Block vs Epidural in Radical Cystectomy | Biotech Hunter | Biotech Hunter