Opioid and Pain Cognition

NACompletedINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

February 1, 2019

Primary Completion Date

March 1, 2021

Study Completion Date

March 1, 2021

Conditions
Pain
Interventions
BEHAVIORAL

Cognitive bias modification

: In CBM, the task presentation and timing is the same as attentional bias, except the probe always replaces the neutral word. It ensures that: 1) the duration of CBM and control training should not differ; 2) CBM and control participants receive equal practice on the motoric aspects of the task; and 3) CBM and control participants are exposed to the same word cues. Based on previous data, duration of CBM and control trainings will be about 10 minutes.

BEHAVIORAL

Standard attentional bias

"the standard attentional bias task, a drug or pain-related word is presented next to a neutral word for 500ms. Subsequently, a probe (i.e., a q or p) replaces the drug/pain word or the neutral word at an equal rate. The participant's task is to indicate the location of the probe as quickly as possible by pressing q or p. Attentional bias is calculated from the difference in reaction times (i.e., neutral cue minus drug/pain cue) to indicate the location of the probe, with higher values indicating greater attentional bias. For all tasks, opioid and pain words will be presented in separate blocks in counterbalanced order. Neutral words paired with opioid or pain words will be matched for length and frequency of use in the English language."

Trial Locations (1)

06516

Veteran Affairs Hospital, West Haven

All Listed Sponsors
collaborator

US Department of Veterans Affairs

FED

lead

Yale University

OTHER

NCT04132609 - Opioid and Pain Cognition | Biotech Hunter | Biotech Hunter