In Vitro Follicle Activation in Patient With Premature Ovarian Failure Under 36 Years Old

NACompletedINTERVENTIONAL
Enrollment

10

Participants

Timeline

Start Date

December 1, 2017

Primary Completion Date

October 15, 2019

Study Completion Date

December 15, 2019

Conditions
Activation of Primordial Follicles
Interventions
PROCEDURE

In vitro activation of primordial follicles by PTEN inhibitor and AKT stimulator

After laparoscopic unilateral oophorectomy, ovarian medulla would be dissected from cortex. After fragmentation of 2 cm square ovarian cortex into smaller pieces they would be incubated PTEN inhibitor and AKT stimulator for 48 hours. Finally we will auto graft these fragments beneath to the fallopian tube peritoneal surface.

Trial Locations (1)

06100

Hacettepe University School of Medicine, Department of Ob/Gyn, Ankara

All Listed Sponsors
collaborator

St. Marianna University School of Medicine

OTHER

collaborator

Stanford University

OTHER

lead

Hacettepe University

OTHER

NCT04131244 - In Vitro Follicle Activation in Patient With Premature Ovarian Failure Under 36 Years Old | Biotech Hunter | Biotech Hunter