Ketamine for Acute Pain Management After Trauma

PHASE4CompletedINTERVENTIONAL
Enrollment

305

Participants

Timeline

Start Date

July 1, 2020

Primary Completion Date

March 30, 2022

Study Completion Date

September 30, 2022

Conditions
Trauma InjuryPainOpioid Use
Interventions
DRUG

Ketamine plus usual care

Bolus of .35 mg/kg Infusion start @ 0.15 mg/kg/hr; titrate range is 0.1 - 0.25 mg/kg/hr for 24 to 48 hours after admission and each subsequent major surgery plus multi-modal pain therapy considered as standard of care. Standard of care medications include Acetaminophen 1000 mg po q6 hours, Naproxen 500 mg po q12 hours, Gabapentin 300 mg po q8 hours and Lidocaine patch q 12 hours.

DRUG

Usual Care

Standard of care medications include Acetaminophen 1000 mg po q6 hours, Naproxen 500 mg po q12 hours, Gabapentin 300 mg po q8 hours and Lidocaine patch q 12 hours.

Trial Locations (1)

77030

The University of Texas Health Science Center at Houston, Houston

All Listed Sponsors
lead

The University of Texas Health Science Center, Houston

OTHER

NCT04129086 - Ketamine for Acute Pain Management After Trauma | Biotech Hunter | Biotech Hunter