MechSens - Dose-response Relationship of in Vivo Ambulatory Load and Mechanosensitive Cartilage Biomarkers

NACompletedINTERVENTIONAL
Enrollment

87

Participants

Timeline

Start Date

January 8, 2020

Primary Completion Date

July 7, 2024

Study Completion Date

July 7, 2024

Conditions
Articular Cartilage Degeneration
Interventions
PROCEDURE

walking stress test

walk for 30 minutes on a treadmill with either one of the three loading conditions (reduced load = 80% Bodyweight (BW), normal load = 100% BW, increased load = 120% BW). The order of experimental condition will be applied in randomized order determined by block randomization, and the same self-selected walking speed will be used for all conditions.

Trial Locations (1)

4031

Department of Orthopaedics and Traumatology, University Hospital Basel, Basel

All Listed Sponsors
collaborator

Swiss National Science Foundation

OTHER

lead

University Hospital, Basel, Switzerland

OTHER

NCT04128566 - MechSens - Dose-response Relationship of in Vivo Ambulatory Load and Mechanosensitive Cartilage Biomarkers | Biotech Hunter | Biotech Hunter