Role of Mitochondrial Dysfunction in the Occurrence of Acute Kidney Injury (AKI) in Postoperative Cardiac Surgery

CompletedOBSERVATIONAL
Enrollment

27

Participants

Timeline

Start Date

October 2, 2019

Primary Completion Date

July 12, 2021

Study Completion Date

January 2, 2022

Conditions
Patients Undergoing Coronary Artery Bypass Graft (CABG) Surgery Requiring Extracorporeal Circulation
Interventions
PROCEDURE

Coronary Artery Bypass Graft (CABG)

Mitochondrial function will be studied on cardiac tissue collected intraoperatively at the time of placement of the ECC cannulas by the surgeon. Fragments from auricle dissection of the right atrium of the patient will be requalified as sample residues, and will be used immediately by the surgeon to measure mitochondrial respiration (measurement of oxygen consumption by oxygenation and permeability test of the external mitochondrial membrane by the addition of cytochrome C in the oxygen chamber).

Trial Locations (1)

97200

CHU de Martinique, Fort-de-France

All Listed Sponsors
lead

University Hospital Center of Martinique

OTHER

NCT04125069 - Role of Mitochondrial Dysfunction in the Occurrence of Acute Kidney Injury (AKI) in Postoperative Cardiac Surgery | Biotech Hunter | Biotech Hunter