Preoperative Nivolumab in Patients With Locally Advanced Colon Cancer (T3 or T4): a Window-of-opportunity Study

PHASE2CompletedINTERVENTIONAL
Enrollment

22

Participants

Timeline

Start Date

June 12, 2018

Primary Completion Date

June 17, 2019

Study Completion Date

September 2, 2019

Conditions
Colon Cancer Stage II/III
Interventions
DRUG

Nivolumab

Locally advanced colon cancer must be documented at screening (within 21 days prior to initiation of study treatment) and re-assessed prior surgery by spiral or multidetector computed tomography (CT) scan Postoperatively, standard adjuvant chemotherapy will be administered in pathological III-stage and at investigator discretion in pathological II-stage at high risk

Trial Locations (1)

80131

Istituto Tumori di Napoli - Fondazione G. Pascale, Napoli

All Listed Sponsors
lead

National Cancer Institute, Naples

OTHER

NCT04123925 - Preoperative Nivolumab in Patients With Locally Advanced Colon Cancer (T3 or T4): a Window-of-opportunity Study | Biotech Hunter | Biotech Hunter