A Phase I/II Trial Investigating LOAd703 in Combination With Atezolizumab in Malignant Melanoma

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

24

Participants

Timeline

Start Date

January 28, 2020

Primary Completion Date

July 30, 2023

Study Completion Date

July 30, 2023

Conditions
Malignant Melanoma
Interventions
GENETIC

delolimogene mupadenorepvec

LOAd703 is an oncolytic adenovirus encoding TMZ-CD40L and 4-1BBL

BIOLOGICAL

atezolizumab

Atezolizumab is an anti-PD-L1 antibody

Trial Locations (3)

75185

Uppsala University Hospital, Uppsala

77030

Baylor St Luke's Medical Center, Houston

90025

Cedars-Sinai Medical Center, The Angeles Clinic and Research Institute, Los Angeles

Sponsors

Lead Sponsor

Collaborators (1)

All Listed Sponsors
collaborator

Precision Oncology LLC

INDUSTRY

lead

Lokon Pharma AB

INDUSTRY

NCT04123470 - A Phase I/II Trial Investigating LOAd703 in Combination With Atezolizumab in Malignant Melanoma | Biotech Hunter | Biotech Hunter