Vaginal Probiotics and Pessaries and Their Impact on the Vaginal Microenvironment

NACompletedINTERVENTIONAL
Enrollment

141

Participants

Timeline

Start Date

October 30, 2019

Primary Completion Date

May 30, 2021

Study Completion Date

May 30, 2021

Conditions
Pelvic Organ ProlapseInflammatory ResponseDysbiosis
Interventions
OTHER

BiopHreshTM vaginal probiotic supplement (Good Clean Love, Inc. Eugene, OR) and RestoreTM gel.

BiopHreshTM is a vaginal probiotic supplement that is offered over the counter and contains four different lactobacilli strains (L. crispatus, L. gasseri, L. jensenii, and L. rhamnosus). RestoreTM is a moisturizing personal lubricant that has been on the market for three years. Participants will use 1 probiotic capsule with RestoreTM gel nightly three times weekly.

OTHER

Standard Care

Standard care arm is standard care for pessary use. Pessary maintenance will be performed standardly by their provider.

Trial Locations (1)

06103

Hartford Hospital, Hartford

All Listed Sponsors
collaborator

University of Maryland

OTHER

collaborator

University of Connecticut

OTHER

lead

Hartford Hospital

OTHER

NCT04118049 - Vaginal Probiotics and Pessaries and Their Impact on the Vaginal Microenvironment | Biotech Hunter | Biotech Hunter