NCT04117893View on ClinicalTrials.gov

Duloxetine Combined With Intra-articular Injection of Corticosteroid and Hyaluronic Acid Reduces Pain in the Treatment of Knee Osteoarthritis Patients

PHASE4CompletedINTERVENTIONAL

Enrollment

150

Participants

Timeline

Start Date

October 1, 2019

Primary Completion Date

June 1, 2021

Study Completion Date

December 31, 2021

Conditions

Osteoarthritis, KneeChronic Pain

Interventions

DRUG

Duloxetine

Participants will start on duloxetine 30 mg per day for one week and then titrated up to duloxetine 60mg per day for 23 weeks.

DRUG

intra-articular injection of corticosteroid and hyaluronic acid

Participants will receive a 3.5 ml intra-articular injection of 30mg of hyaluronic acid plus 10mg of triamcinolone acetonide.

Trial Locations (1)

100070

Beijing Tiantan Hospital, Beijing

All Listed Sponsors

lead

Beijing Tiantan Hospital

OTHER

NCT04117893 - Duloxetine Combined With Intra-articular Injection of Corticosteroid and Hyaluronic Acid Reduces Pain in the Treatment of Knee Osteoarthritis Patients | Biotech Hunter | Biotech Hunter