NCT04116502 - MITHRIDATE: Ruxolitinib Versus Hydroxycarbamide or Interferon as First Line Therapy in High Risk Polycythemia Vera | Biotech Hunter

Enrollment

586

Participants

Timeline

Start Date

October 25, 2019

Primary Completion Date

October 31, 2028

Study Completion Date

April 1, 2030

Conditions

Polycythemia Vera

Interventions

DRUG

Ruxolitinib

10mg of ruxolitinib twice daily (bd)

DRUG

Hydroxycarbamide

Via standard hospital mechanisms

DRUG

Interferon-Alpha

Any formulation, via standard hospital mechanisms

Trial Locations (47)

AB25 2ZN

RECRUITING

Aberdeen Royal Infirmary, Aberdeen

BA1 3NG

RECRUITING

Royal United Hospital, Bath

BT9 7AB

RECRUITING

Belfast City Hospital, Belfast

B9 5SS

RECRUITING

Birmingham Heartlands Hospital, Birmingham

FY3 8NR

RECRUITING

Blackpool Victoria Hospital, Blackpool

BH7 7DW

RECRUITING

Royal Bournemouth Hospital, Bournemouth

BS10 5NB

RECRUITING

Southmead Hospital, Bristol

CB2 0QQ

RECRUITING

Addenbrooke's Hospital, Cambridge

CT1 3NG

RECRUITING

Kent and Canterbury Hospital, Canterbury

CF14 4XW

RECRUITING

University Hospital of Wales, Cardiff

PO19 6SE

RECRUITING

St Richard's Hospital, Chichester

CO4 5JL

RECRUITING

Colchester Hospital, Colchester

HU16 5JQ

RECRUITING

Castle Hill Hospital, Cottingham

DY1 2HQ

RECRUITING

Russells Hall Hospital, Dudley

EH4 2XU

RECRUITING

Western General Hospital, Edinburgh

EX2 5DW

RECRUITING

Royal Devon and Exeter Hospital, Exeter

GL1 3NN

RECRUITING

Gloucestershire Royal Hospital, Gloucester

HX3 0PW

ACTIVE_NOT_RECRUITING

Calderdale Royal Hospital, Halifax

HD3 3EA

ACTIVE_NOT_RECRUITING

Huddersfield Royal Infirmary, Huddersfield

IV2 3UJ

RECRUITING

Raigmore Hospital, Inverness

NN16 8UZ

RECRUITING

Kettering General Hospital, Kettering

LE1 5WW

RECRUITING

Leicester Royal Infirmary, Leicester

EH54 6PP

RECRUITING

St John's Hospital, Livingston

NW1 2BU

RECRUITING

University College Hospital, London

SE1 9RT

RECRUITING

Guy's Hospital, London

SW17 0QT

RECRUITING

St George's Hospital, London

M23 9LT

RECRUITING

Wythenshawe Hospital, Manchester

CH49 5PE

RECRUITING

Arrowe Park Hospital, Metropolitan Borough of Wirral

TS4 3BW

RECRUITING

The James Cook University Hospital, Middlesbrough

NE7 7DN

RECRUITING

Freeman Hospital, Newcastle upon Tyne

NP20 2UB

RECRUITING

Royal Gwent Hospital, Newport

NE29 8NH

RECRUITING

North Tyneside General Hospital, North Shields

NN1 5BD

RECRUITING

Northampton General Hospital, Northampton

NR4 7UY

RECRUITING

Norfolk and Norwich University Hospital, Norwich

NG5 1PB

RECRUITING

Nottingham City Hospital, Nottingham

OX3 7LE

RECRUITING

Churchill Hospital, Oxford

RG1 5AN

RECRUITING

Royal Berkshire Hospital, Reading

WA7 2DA

RECRUITING

Halton Hospital, Runcorn

SL2 4HL

RECRUITING

Wexham Park Hospital, Slough

SO16 6YD

RECRUITING

Southampton General Hospital, Southampton

ST4 6QG

RECRUITING

Royal Stoke University Hospital, Stoke-on-Trent

SR4 7TP

RECRUITING

Sunderland Royal Hospital, Sunderland

B75 7RR

RECRUITING

Good Hope Hospital, Sutton Coldfield

TR1 3LJ

RECRUITING

Royal Cornwall Hospital, Truro

CV34 5BW

RECRUITING

Warwick Hospital, Warwick

WV10 0QP

RECRUITING

New Cross Hospital, Wolverhampton

BN11 2DH

RECRUITING

Worthing Hospital, Worthing