50
Participants
Start Date
April 1, 2019
Primary Completion Date
April 30, 2025
Study Completion Date
November 30, 2026
Hemodynamic management based on invasive fluid responsiveness parameters
In case of hypotension (reduction of MAP for more than 15% of individual blood pressure) the SPV value more than 8% will be used as a trigger for the bolus of 2 ml/kg of Plasmalyte (Baxter)
Hemodynamic management based on noninvasive cardiac output and SVV measurement
In case of hypotension (reduction of MAP for more than 15% of individual blood pressure) the systemic vascular resistance (SVR) value will be used to trigger norepinephrine infusion. In patients with low SVR norepinephrine infusion will be started. In patients with high SVR value either fluid bolus (in patient with SVV value above 8%), or dobutamine infusion (in patients with SVV value below or equal 8%) will be used.
RECRUITING
University Hospital Hradec Kralove, Hradec Králové
University Hospital Hradec Kralove
OTHER