Functionally Validated Structural Endpoints for Early AMD

CompletedOBSERVATIONAL
Enrollment

556

Participants

Timeline

Start Date

October 7, 2019

Primary Completion Date

July 1, 2024

Study Completion Date

October 31, 2024

Conditions
Age-related Macular DegenerationAging
Interventions
OTHER

Normal Macular Health

This group of participants will have function assessed using rod- and cone-mediated tests (rod-mediated dark adaptation, 2 color dark adapted perimetry, cone-mediated perimetry, photopic and mesopic acuity, photopic and mesopic contrast sensitivity). Age-related macular degeneration status will be determined by multi-modal imaging.

OTHER

Early Macular Degeneration

This group of participants will have function assessed using rod- and cone-mediated tests (rod-mediated dark adaptation, 2 color dark adapted perimetry, cone-mediated perimetry, photopic and mesopic acuity, photopic and mesopic contrast sensitivity). Age-related macular degeneration status will be determined by multi-modal imaging.

OTHER

Young Normals

This group of participants will have function assessed using rod- and cone-mediated tests (rod-mediated dark adaptation, 2 color dark adapted perimetry, cone-mediated perimetry, photopic and mesopic acuity, photopic and mesopic contrast sensitivity). Age-related macular degeneration status will be determined by multi-modal imaging.

Trial Locations (1)

35294

University of Alabama at Birmingham, Birmingham

All Listed Sponsors
collaborator

National Eye Institute (NEI)

NIH

collaborator

National Institutes of Health (NIH)

NIH

lead

Cynthia Owsley

OTHER

NCT04112667 - Functionally Validated Structural Endpoints for Early AMD | Biotech Hunter | Biotech Hunter