Left Bundle Branch Pacing Versus Biventricular Pacing for Cardiac Resynchronization Therapy

NACompletedINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

November 14, 2019

Primary Completion Date

June 29, 2021

Study Completion Date

June 29, 2021

Conditions
Chronic Heart Failure
Interventions
PROCEDURE

Left bundle branch pacing

Successful LBBP was defined as (1) LBBP lead is located at 1.5-2cm from His-bundle towards right ventricular apex; (2) Paced QRS morphology of right bundle branch delay(CRBBD) in lead V1; (3) Stimulus to the peak of R wave in V5 and V6 QRS wave, which represents left ventricular activation time(Stim-LVAT), is less than 100ms and constant at high and low output pacing; (4) Unipolar pacing threshold\<1.5V/0.5ms; (5) Recording P potential when narrow QRS escape rhythm or CRBBB escape rhythm(not essential).

PROCEDURE

Biventricular pacing

Implantation of a LV pacing lead is attempted using the standard-of-care technique first.

Trial Locations (2)

210029

The First Affiliated Hospital with Nanjing Medical University, Nanjing

Unknown

Fu Wai Hospital, Beijing, China, Beijing

All Listed Sponsors
collaborator

Fu Wai Hospital, Beijing, China

OTHER

lead

The First Affiliated Hospital with Nanjing Medical University

OTHER

NCT04110431 - Left Bundle Branch Pacing Versus Biventricular Pacing for Cardiac Resynchronization Therapy | Biotech Hunter | Biotech Hunter