794
Participants
Start Date
January 29, 2020
Primary Completion Date
July 13, 2023
Study Completion Date
July 13, 2023
Preoperative Education
Brochure and video about relevance of postoperative pulmonary complications, postoperative mobilization and use of incentive spirometry.
Intraoperative PEEP (Positive End-Expiratory Pressure) Individualization
PEEP will be set by maximizing respiratory system compliance along a decremental PEEP titration following an incremental recruitment maneuver.
Individualization of Neuromuscular Blockade
Administration of neuromuscular blocking agents and their reversal will be done based on established protocol.
Postoperative Incentive Spirometry
Participants will be encouraged to adhere to incentive spirometry to be started 2 hours after surgery and maintained until participant freely ambulates. Supervision will be provided 3 times/day for continuous education and management of barriers to optimal performance.
Postoperative Ambulation
Participants will be encouraged to adhere to prescription of early ambulation.
Columbia University Medical Center, New York
Memorial Sloan Kettering, New York
Montefiore Hospital, The Bronx
University of Rochester, Rochester
Duke University, Durham
South Florida Veterans Affairs Foundation for Research and Education, Inc., Miami
Mayo Clinic, Rochester
Northwestern University, Evanston
University of Nebraska Medical Center, Omaha
University of Colorado, Anschutz Medical Campus, Aurora
University of California - San Francisco, San Francisco
Stanford University, Stanford
Massachusetts General Hospital, Boston
Brigham and Women's Hospital, Boston
Beth Israel Deaconess Hospital, Boston
Univerisity of Massachusetts Amherst Center, Worcester
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Columbia University
OTHER