Diagnostic Value of Ultra-low Dose Thoracic Scanner for the Pulmonary Arteriovenous Malformation Detection in HHT Patient

NACompletedINTERVENTIONAL
Enrollment

45

Participants

Timeline

Start Date

November 28, 2019

Primary Completion Date

May 28, 2021

Study Completion Date

May 28, 2021

Conditions
Telangiectasia, Hereditary HemorrhagicRendu Osler Disease
Interventions
RADIATION

Low CT scanner without injection dose

CT scan acquisition will be performed at 140 kVp (kilovolt peak), 10 mAs(milliampere), CTDI 1.3 mGy with an irradiation dose 0.51 mSv (milliSievert). The CT image will be reconstructed and analyzed in parenchyma window. The CT images will be blinded and re-read by two independent senior radiologists 3 to 6 weeks apart between each re-reading.

RADIATION

Ultra-low dose CT scanner without injection

CT acquisition will be performed at 80 kVp for patient with a body mass index\<30, and 100 kVp with a body mass index\>30, 10 mAs, CTDI 0.3 and 0.6 mGy with an irradiation dose 0.15-0.30 mSv. The CT images will be reconstructed and analyzed in mediastinal window. The CT images will be blinded and re-read by two independent senior radiologists 3 to 6 weeks apart between each re-reading.

Trial Locations (1)

69500

Hospices Civils de Lyon - Hopital Louis Pradel, Bron

All Listed Sponsors
lead

Hospices Civils de Lyon

OTHER

NCT04108052 - Diagnostic Value of Ultra-low Dose Thoracic Scanner for the Pulmonary Arteriovenous Malformation Detection in HHT Patient | Biotech Hunter | Biotech Hunter