Brain Stimulation And Group Therapy to Improve Gesture and Social Skills in Psychosis (BrAGG-SoS)

NACompletedINTERVENTIONAL
Enrollment

73

Participants

Timeline

Start Date

December 1, 2019

Primary Completion Date

April 24, 2024

Study Completion Date

April 24, 2024

Conditions
Schizophrenia
Interventions
DEVICE

continuous theta burst stimulation (cTBS)

"cTBS stimulation of 17 mins over right inferior parietal lobe (IPL) with two 44 s stimulations separated by 15 mins, 10 sessions in total (5 per week). intensity will be 100% of resting motor threshold at 30 Hz.~administered in weeks 1 and 2 of the trial"

DEVICE

placebo cTBS

"Placebo stimulation of 17 mins over right IPL with two 44 s stimulations separated by 15 mins, 10 sessions in total (5 per week). intensity will be 0% of resting motor threshold at 30 Hz.~administered in weeks 1 and 2 of the trial"

BEHAVIORAL

social cognitive remediation therapy (SCRT)

16 sessions of group SCRT will be scheduled within 8 weeks, comprising 6-8 participants per group with 2 therapists. Duration of group sessions will be 60-90 mins. The content will follow the manual of SCRT and we will add a short intervention to practice the use of co-speech gestures at each session

BEHAVIORAL

Sham group therapy

Group activities in closed groups of 6 participants. Schedule of two sessions per week for 8 weeks. Two therapists are guiding different leisure activities, e.g. group walks, going to museums/movies, games.

Trial Locations (1)

3000

University of Bern, Translational Research Center, University Hospital of Psychiatry, Bern

All Listed Sponsors
lead

University of Bern

OTHER

NCT04106427 - Brain Stimulation And Group Therapy to Improve Gesture and Social Skills in Psychosis (BrAGG-SoS) | Biotech Hunter | Biotech Hunter