Pre-therapeutic MRI Assessment of Early-Stage Rectal Cancer and Significant Rectal Polyps to Avoid Major Resectional Surgery

NARecruitingINTERVENTIONAL
Enrollment

200

Participants

Timeline

Start Date

September 1, 2024

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2031

Conditions
Rectal CancerColo-rectal Cancer
Interventions
DIAGNOSTIC_TEST

MRI scan

MRI scans will be recommended for all rectal polyps ≥20mm in size, or with other features suspicious of malignancy, prior to removal. This is designed to reduce the numbers of Early Rectal Cancers missed in endoscopy.

OTHER

Radiologist training

Radiologist training in the use of the PRESERVE mrSRT for suspected Early Rectal Cancer.

Trial Locations (23)

RG1 5AN

NOT_YET_RECRUITING

Royal Berkshire Hospital, Reading

AMERSHAM

RECRUITING

Buckinghamshire Healthcare Nhs Trust, Amersham

NW1 2PG

NOT_YET_RECRUITING

University College London Hospitals Nhs Foundation Trust, London

SE5 9RS

NOT_YET_RECRUITING

King'S College Hospital Nhs Foundation Trust, London

SW10 9NH

NOT_YET_RECRUITING

West Middlesex Hospital, London

W2 1BL

NOT_YET_RECRUITING

Imperial College Healthcare Nhs Trus, London

UB8 3NN

NOT_YET_RECRUITING

The Hillingdon Hospitals Nhs Foundation Trust, Uxbridge

RG24 9NA

NOT_YET_RECRUITING

Hampshire Hospitals Nhs Foundation Trust, Basingstoke

SO16 6YD

NOT_YET_RECRUITING

Southampton General Hospital, Southampton

CT1 3NG

NOT_YET_RECRUITING

Kent & Canterbury Hospital, Canterbury

ME16 9QQ

NOT_YET_RECRUITING

Maidstone Hospital, Maidstone

LA9 7RG

NOT_YET_RECRUITING

Westmorland General Hospital, Kendal

LE1 5WW

NOT_YET_RECRUITING

Leicester Royal Infirmary, Leicester

SW17 0QT

NOT_YET_RECRUITING

St George'S Hospital, Tooting

OX3 9DU

NOT_YET_RECRUITING

John Radcliffe Hospital, Oxford

ST16 2LP

NOT_YET_RECRUITING

Nhs Staffordshire and Stoke-on-Trent Integrated Care Board, Stafford

GU16 7UJ

NOT_YET_RECRUITING

Frimley Health Nhs Foundation Trust, Camberley

SM5 1AA

NOT_YET_RECRUITING

St Helier Hospital, Carshalton

KT2 7QB

NOT_YET_RECRUITING

Kingston Hospital Nhs Foundation Trust, Kingston upon Thames

CR7 7YE

NOT_YET_RECRUITING

Croydon Health Services Nhs Trust, Thornton Heath

SA11 3LX

NOT_YET_RECRUITING

Tonna Hospital, Swansea

SP2 8BJ

NOT_YET_RECRUITING

Salisbury District Hospital, Salisbury

HA1 3UJ

NOT_YET_RECRUITING

St Marks Bowel Cancer Screening Centre, Harrow

All Listed Sponsors
collaborator

Pelican Cancer Foundation

OTHER

collaborator

RM Partners West London Cancer Alliance

UNKNOWN

lead

Imperial College London

OTHER