4,500
Participants
Start Date
June 10, 2005
Primary Completion Date
March 31, 2028
Study Completion Date
March 31, 2028
RECRUITING
Queen Elizabeth The Queen Mother Hospital, Canterbury
RECRUITING
Whiston Hospital, Prescot
RECRUITING
Nevill Hall Hospital, Aneurin Bevan University Health Board, Abergavenny
RECRUITING
Stoke Mandeville Hospital, Buckinghamshire Healthcare NHS Trust, Aylesbury
COMPLETED
Barnsley Hospital, Barnsley Hospital NHS Foundation Trust, Barnsley
RECRUITING
Basildon University Hospital, Basildon and Thurrock University Hospitals NHS Foundation Trust, Basildon
RECRUITING
Basingstoke and North Hampshire Hospital, Hampshire Hospitals NHS Foundation Trust, Basingstoke
RECRUITING
Royal National Hospital for Rheumatic Diseases, Royal United Hospitals Bath NHS Foundation Trust, Bath
RECRUITING
Birmingham Heartlands Hospital, University Hospitals Birmingham NHS Foundation Trust, Birmingham
RECRUITING
Queen Elizabeth Hospital Birmingham, University Hospitals Birmingham NHS Foundation Trust, Birmingham
RECRUITING
Bristol Royal Infirmary, University Hospitals Bristol NHS Foundation Trust, Bristol
RECRUITING
Queen's Hospital, University Hospitals of Derby and Burton NHS Foundation Trust, Burton-on-Trent
RECRUITING
West Suffolk Hospital, West Suffolk NHS Foundation Trust, Bury St Edmunds
RECRUITING
Addenbrookes Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge
RECRUITING
Chelsea and Westminster Hospital, Chelsea and Westminster Hospital NHS Foundation Trust, Chelsea
RECRUITING
West Middlesex University Hospital, Chelsea and Westminster Hospital NHS Foundation Trust, Chelsea
RECRUITING
Ashford and St Peter's Hospitals, Ashford & St Peter's Hospitals NHS Foundation Trust, Chertsey
RECRUITING
Countess of Chester Hospital, Countess of Chester NHS Foundation Trust, Chester
RECRUITING
Christchurch Hospital, University Hospitals Dorset NHS Foundation Trust, Christchurch
RECRUITING
Croydon University Hospital, Croydon Health Service NHS Trust, Croydon
RECRUITING
Darlington Memorial Hospital, County Durham and Darlington NHS Foundation Trust, Darlington
RECRUITING
Royal Derby Hospital, University Hospitals of Derby and Burton NHS Foundation Trust, Derby
RECRUITING
Doncaster Royal Infirmary, Doncaster and Bassetlaw Hospitals NHS Foundation Trust, Doncaster
COMPLETED
Ninewells Hospital and Medical School, NHS Tayside, Dundee
RECRUITING
Royal Devon and Exeter Hospital, Royal Devon and Exeter NHS Foundation Trust, Exeter
COMPLETED
Frimley Park Hospital, Frimley Park Hospital NHS Foundation Trust, Frimley
RECRUITING
Gateshead Queen Elizabeth Hospital, Gateshead Health NHS Foundation Trust, Gateshead
COMPLETED
Inverclyde Royal Hospital, NHS Greater Glasgow and Clyde, Glasgow
COMPLETED
Royal Alexandra Hospital, NHS Greater Glasgow and Clyde, Glasgow
COMPLETED
Vale of Leven Hospital, NHS Greater Glasgow and Clyde, Glasgow
COMPLETED
James Paget Hospital, James Paget University Hospitals NHS Foundation Trust, Great Yarmouth
COMPLETED
Royal Surrey County Hospital, Royal Surrey County Hospital NHS Foundation Trust, Guildford
RECRUITING
Harrogate and District Hospital, Harrogate and District NHS Foundation Trust, Harrogate
RECRUITING
Hull Royal Infirmary, Hull and East Yorkshire NHS Trust, Hull
COMPLETED
Ipswich Hospital, East Suffolk and North Essex NHS Foundation Trust, Ipswich
RECRUITING
Airedale General Hospital, Airedale NHS Foundation Trust, Keighley
RECRUITING
Westmorland General Hospital, University Hospitals of Morecambe Bay NHS Foundation Trust, Kendal
COMPLETED
The Queen Elizabeth Hospital, The Queen Elizabeth Hospital Kings Lynn NHS Foundation Trust, Kings Lynn
RECRUITING
Royal Lancaster Infirmary, University Hospitals of Morecambe NHS Foundation Trust, Lancaster
RECRUITING
Chapel Allerton Hospital, Leeds Teaching Hospitals NHS Foundation Trust, Leeds
RECRUITING
Leicester Royal Infirmary, University Hospitals of Leicester NHS Trust, Leicester
RECRUITING
Aintree University Hospital, Aintree University Hospitals NHS Trust, Liverpool
RECRUITING
Royal Glamorgan Hospital, Cwm Taf University Health Board, Llantrisant
RECRUITING
Hammersmith Hospital, Imperial College Healthcare NHS Trust, London
RECRUITING
King's College Hospital, King's College Hospital NHS Foundation Trust, London, London
RECRUITING
Royal Free Hospital, Royal Free NHS Foundation Trust, London
RECRUITING
St George's Hospital, St George's University Hospitals NHS Foundation Trust, London
RECRUITING
University College London Hospital, University College London NHS Foundation Trust, London
RECRUITING
Manchester Royal Infirmary, Manchester University NHS Foundation Trust, Manchester
RECRUITING
Arrowe Park Hospital, Wirral University Hospital NHS Foundation Trust, Metropolitan Borough of Wirral
RECRUITING
Freeman Hospital, The Newcastle-upon-Tyne Hospitals NHS Foundation Trust, Newcastle
RECRUITING
North Tyneside General Hospital, Northumbria Healthcare NHS Foundation Trust, North Shields
RECRUITING
Northampton General Hospital, Northampton General Hospital NHS Trust, Northampton
COMPLETED
Norfolk and Norwich University Hospital, Norfolk and Norwich University Hospitals NHS Foundation Trust, Norwich
RECRUITING
Queens Medical Centre, Nottingham University Hospitals NHS Trust, Nottingham
NOT_YET_RECRUITING
Oxford Nuffield Orthopaedic Centre, Oxford University Hospitals NHS Trust, Oxford
RECRUITING
Peterborough City Hospital, North West Anglia NHS Foundation Trust, Peterborough
RECRUITING
Derriford Hospital, University Hospital Plymouth NHS Trust, Plymouth
RECRUITING
Poole Hospital, University Hospitals Dorset NHS Foundation Trust, Poole
RECRUITING
Minerva Health Centre, Lancashire and South Cumbria NHS Foundation Trust, Preston
RECRUITING
Royal Preston Hospital, Lancashire Teaching Hospitals NHS Foundation Trust, Preston
RECRUITING
Salford Royal Hospital, Salford Royal NHS Foundation Trust, Salford
RECRUITING
Scarborough General Hospital, York and Scarborough Teaching Hospitals NHS Foundation Trust, Scarborough
RECRUITING
Southend University Hospital, Southend University Hospital NHS Foundation Trust, Southend-on-Sea
RECRUITING
Lister Hospital, East and North Hertfordshire NHS Trust, Stevenage
RECRUITING
Haywood Hospital, Midlands Partnership NHS Foundation Trust, Stoke-on-Trent
RECRUITING
Great Western Hospital, The Great Western Hospitals NHS Foundation Trust, Swindon
COMPLETED
Torbay Hospital, Torbay and South Devon NHS Foundation Trust, Torquay
RECRUITING
Royal Cornwall Hospital, Royal Cornwall Hospitals NHS Trust, Truro
RECRUITING
Pinderfields Hospital, Mid Yorkshire Hospitals NHS Trust, Wakefield
RECRUITING
Warrington Hospital, Warrington and Halton Hospitals NHS Foundation Trust, Warrington
COMPLETED
Warwick Hospital, South Warwickshire NHS Foundation Trust, Warwick
RECRUITING
Royal Hampshire County Hospital, Hampshire Hospitals NHS Foundation Trust, Winchester
RECRUITING
University Hospital Wishaw, NHS Lanarkshire, Wishaw
COMPLETED
York Hospital, York and Scarborough Teaching Hospitals NHS Foundation Trust, York
RECRUITING
Betsi Cadwaladr University Health Board, Bangor
University of Oxford
OTHER
University of Leeds
OTHER