Repetitive Transcranial Magnetic Stimulation and Multi-modality Aphasia Therapy for Post-stroke Non-fluent Aphasia

NACompletedINTERVENTIONAL
Enrollment

46

Participants

Timeline

Start Date

April 15, 2021

Primary Completion Date

August 21, 2023

Study Completion Date

August 24, 2023

Conditions
StrokeAphasia, Non-fluent
Interventions
DEVICE

1Hz inhibitory rTMS

20 minutes of 1Hz (1200 pulses) repetitive transcranial magnetic stimulation (rTMS) applied by Magstim Rapid 2 stimulator equipped with an airfilm figure-8 coil

DEVICE

1Hz sham rTMS

20 minutes of 1Hz (1200 pulses) repetitive transcranial magnetic stimulation (rTMS) applied by Magstim Rapid 2 stimulator equipped with an airfilm figure-8 sham coil.

BEHAVIORAL

Multi-Modality Aphasia Therapy (M-MAT)

Participants receive 3.5 hours of intensive speech therapy in small groups delivered by a blinded speech language pathologist and therapy assistant. The objective of M-MAT is to improve word production through shaping of responses (ie. Gradually increasing complexity of spoken targets towards eventual mastery) and social-mediated repetitive practice. Therapists use game-based interactive tasks and rich multi-modal cueing (gestures, written words, drawing, reading words) to improve spoken production and oral communication.

Trial Locations (1)

T2N 2T9

Foothills Medical Centre, Calgary

All Listed Sponsors
lead

University of Calgary

OTHER