A Study of Nivolumab or Placebo in Combination With Docetaxel in Men With Advanced Castration-resistant Prostate Cancer

PHASE3CompletedINTERVENTIONAL
Enrollment

1,030

Participants

Timeline

Start Date

February 6, 2020

Primary Completion Date

June 1, 2023

Study Completion Date

June 25, 2024

Conditions
Prostate Cancer
Interventions
BIOLOGICAL

Nivolumab

Specified dose on specified days

DRUG

Prednisone

Specified dose on specified days

DRUG

Docetaxel

Specified dose on specified days

OTHER

Placebo

Specified dose on specified days

Trial Locations (293)

0

Local Institution - 0025, Santiago

404

Local Institution - 0194, Taichung

704

Local Institution - 0386, Tainan City

833

Local Institution - 0192, Niaosng

852

Local Institution - 0145, Hong Kong

1020

Local Institution - 0157, Vienna

1070

Local Institution - 0122, Anderlecht

1090

Local Institution - 0131, Vienna

1234

Local Institution - 0378, Providencia

1280

Local Institution - 0077, Buenos Aires

1426

Local Institution - 0178, Buenos Aires

2076

Local Institution - 0132, Wahroonga

2145

Local Institution - 0127, Westmead

2250

Local Institution - 0152, Gosford

2300

Local Institution - 0137, Turnhout

2480

Local Institution - 0091, Lismore

2610

Local Institution - 0029, Wilrijk

3100

Local Institution - 0017, Mexico City

3112

Local Institution - 0102, Tauranga

3144

Local Institution - 0032, Malvern

3199

Local Institution - 0040, Frankston

3204

Local Institution - 0101, Hamilton

3350

Local Institution - 0379, Ballarat

3722

Local Institution - 0374, Seodaemun-Gu

4020

Local Institution - 0118, Linz

4101

Local Institution - 0006, South Brisbane

4102

Local Institution - 0084, Woolloongabba

4414

Local Institution - 0184, Palmerston North

5000

Local Institution - 0153, Parana

5006

Local Institution - 0010, North Adelaide

5020

Local Institution - 0038, Salzburg

5800

Local Institution - 0393, Río Cuarto

6100

Local Institution - 0130, Ankara

6591

Local Institution - 0373, Seoul

8000

Local Institution - 0121, Bruges

8243

Local Institution - 0141, Manresa

8500

Local Institution - 0083, Viedma

8908

Local Institution - 0123, Barcelona

9000

Local Institution - 0114, Ghent

Local Institution - 0162, Ghent

10002

Local Institution - 0175, Taipei

10043

Local Institution - 0070, Orbassano

11776

Local Institution - 0028, Port Jefferson Station

12208

Local Institution - 0300, Albany

13620

Local Institution - 0186, Songnam-si

14004

Local Institution - 0360, Córdoba

15232

Local Institution - 0292, Pittsburgh

17007

Local Institution - 0044, Girona

19004

Local Institution - 0074, Bala-Cynwyd

20141

Local Institution - 0066, Milan

20246

Local Institution - 0064, Hamburg

20613

Local Institution - 0332, Brandywine

21079

Local Institution - 0398, Dijon

21201

Local Institution - 0150, Baltimore

22763

Local Institution - 0069, Hamburg

24127

Local Institution - 0001, Bergamo

25123

Local Institution - 0039, Brescia

26100

Local Institution - 0053, Cremona

27003

Local Institution - 0034, Lugo

28006

Local Institution - 0076, Madrid

28033

Local Institution - 0024, Madrid

28034

Local Institution - 0003, Madrid

28041

Local Institution - 0031, Madrid

28222

Local Institution - 0364, Madrid

29200

Local Institution - 0202, Brest

29414

Local Institution - 0233, Charleston

30029

Local Institution - 0068, Nîmes

30060

Local Institution - 0126, Marietta

30342

Local Institution - 0117, Atlanta

31792

Local Institution - 0382, Thomasville

32256

Local Institution - 0397, Jacksonville

32503

Local Institution - 0285, Pensacola

32806

Local Institution - 0181, Orlando

33021

Local Institution - 0196, Hollywood

33331

Local Institution - 0177, Weston

33805

Local Institution - 0164, Lakeland

34070

Local Institution - 0395, Montpellier

34098

Local Institution - 0113, Istanbul

34295

Local Institution - 0109, Montpellier

35015

Local Institution - 0297, Jung-gu

35043

Local Institution - 0372, Marburg

35575

Local Institution - 0104, Izmir

38122

Local Institution - 0067, Trento

38138

Local Institution - 0149, Germantown

39120

Local Institution - 0004, Magdeburg

40138

Local Institution - 0111, Bologna

40202

Local Institution - 0302, Louisville

40225

Local Institution - 0376, Düsseldorf

40705

Local Institution - 0371, Taichung

41013

Local Institution - 0363, Seville

42601

Local Institution - 0391, Daegu

43126

Local Institution - 0037, Parma

43210

Local Institution - 0333, Columbus

44280

Local Institution - 0112, Malatya

45030

Local Institution - 0015, Zapopan

45070

Local Institution - 0016, Zapopan

46804

Local Institution - 0183, Fort Wayne

48149

Local Institution - 0036, Münster

49055

Local Institution - 0107, Angers

50612

Local Institution - 0158, Yangsan

51100

Local Institution - 0399, Reims

53127

Local Institution - 0089, Bonn

56068

Local Institution - 0014, Koblenz

56126

Local Institution - 0199, Pisa

58128

Local Institution - 0375, Jeollanam-do

58260

Local Institution - 0062, Morelia

59020

Local Institution - 0079, Lille

60590

Local Institution - 0018, Frankfurt am Main

60714

Local Institution - 0287, Niles

67000

Local Institution - 0387, Strasbourg

67200

Local Institution - 0105, Strasbourg

68130

Local Institution - 0299, Omaha

69120

Local Institution - 0389, Heidelberg

69310

Local Institution - 0133, Pierre-Bénite

70852

Local Institution - 0088, Ostrava

72000

Local Institution - 0167, Le Mans

72076

Local Institution - 0169, Tübingen

72401

Local Institution - 0269, Jonesboro

72622

Local Institution - 0023, Nürtingen

75013

Local Institution - 0381, Paris

75014

Local Institution - 0106, Paris

75015

Local Institution - 0071, Paris

75251

Local Institution - 0286, Austin

Local Institution - 0303, Dallas

75701

The University of Texas Health Science Center at Tyler DBA UT Health East Texas Hope Cancer Center, Tyler

78229

Local Institution - 0011, San Antonio

79312

Local Institution - 0172, Emmendingen

80131

Local Institution - 0120, Napoli

81675

Local Institution - 0204, München

82100

Local Institution - 0099, Benevento

83400

Local Institution - 0030, Hyères

85724

Local Institution - 0293, Tucson

90277

Local Institution - 0260, Redondo Beach

90404

Local Institution - 0081, Santa Monica

91054

Local Institution - 0142, Erlangen

92270

Local Institution - 0055, Rancho Mirage

92868

Local Institution - 0179, Orange

94805

Local Institution - 0271, Villejuif

98109

Local Institution - 0110, Seattle

99208

Local Institution - 0289, Spokane

99503

Local Institution - 0012, Anchorage

100020

Local Institution - 0245, Beijing

100034

Local Institution - 0140, Beijing

100036

Local Institution - 0254, Beijing

100050

Local Institution - 0337, Beijing

100071

Local Institution - 0312, Beijing

100730

Local Institution - 0345, Beijing

110042

Local Institution - 0161, Shenyang

111217

Local Institution - 0188, Taipei

115478

Federal State Budgetary Institution N.N. Blokhin National Medical Research Center of Oncology of the, Moscow

119435

Sechenov University, Moscow

125284

P.A. Herzen Moscow Oncology Research Institute, Moscow

143442

Clinical Hospital MEDSI in Otradnoye, Krasnogorsk Moscow Region

150081

Local Institution - 0224, Harbin

163045

SBHI Arkhangelsk Region - Arkhangelsk Clinical Oncological Dispensary, Arkhangelsk

SAHI Republican Clinical Oncology Dispensary of MoH of RT, Kazan'

169610

Local Institution - 0116, Singapore

197136

Andros Clinic LLC, Saint Petersburg

197758

Russian Scientific Centre of Radiology and Surgical Technologies n.a. acad. M.A., Saint Petersburg

200032

Local Institution - 0155, Shanghai

200347

Local Institution - 0052, Craiova

210000

Local Institution - 0165, Nanjing

210009

Local Institution - 0317, Nanjing

Local Institution - 0325, Nanjing

249036

FSBI National Medical Research Radiology Center NMRRC - A. Tsyb Medical Radiological Research Centre, Obninsk

250012

Local Institution - 0326, Jinan

258499

Local Institution - 0005, Singapore

300425

Local Institution - 0035, Timișoara

308430

Local Institution - 0170, Singapore

310003

Local Institution - 0316, Hangzhou

310014

Local Institution - 0344, Hangzhou

330006

Local Institution - 0347, Nanchang

330029

Local Institution - 0330, Nanchang

350001

Local Institution - 0256, Fuzhou

400015

Local Institution - 0041, Cluj-Napoca

Local Institution - 0043, Cluj-Napoca

410031

Local Institution - 0168, Changsha

430000

Local Institution - 0313, Wuhan

450003

Local Institution - 0314, Henan Sheng

Local Institution - 0275, Zhengzhou

510000

Local Institution - 0319, Guangzhou

608648

Local Institution - 0296, Sapporo

610041

Local Institution - 0253, Chengdu

644013

Budgetary Healthcare Institution of Omsk Region &quot,Clinical Oncological Dispensary&quot,, Omsk

710061

Local Institution - 0353, Xi'an

830011

Local Institution - 0310, Ürümqi

900591

Local Institution - 0020, Constanța

1608582

Local Institution - 0308, Tokyo

2320024

Local Institution - 0283, Yokohama

2520598

Local Institution - 0027, Viña del Mar

3109601

Local Institution - 0072, Haifa

4428164

Local Institution - 0368, Kfar Saba

4678602

Local Institution - 0362, Nagoya

4941492

Local Institution - 0128, Petah Tikva

5265601

Local Institution - 0135, Ramat Gan

5418567

Local Institution - 0343, Osaka

5898511

Local Institution - 0323, Ōsaka-sayama

6348522

Local Institution - 0355, Kashihara-shi

6423906

Local Institution - 0138, Tel Aviv

7000914

Local Institution - 0354, Okayama

7500653

Local Institution - 0377, Santiago

7550046

Local Institution - 0282, Ube Shi

7630372

Local Institution - 0026, Santiago

8128582

Local Institution - 0280, Fukuoka

8528501

Local Institution - 0341, Nagasaki

9112001

Local Institution - 0388, Jerusalem

9300194

Local Institution - 0279, Toyama

30110022

Local Institution - 0097, Belo Horizonte

30130090

Local Institution - 0022, Belo Horizonte

80810050

Local Institution - 0082, Curitiba

36608-1753

Local Institution - 0305, Mobile

80211-5222

Local Institution - 0087, Denver

06516-5907

Local Institution - 0190, West Haven

20010-3017

Local Institution - 0366, Washington D.C.

08816

Local Institution - 0365, East Brunswick

07932

Local Institution - 0139, Florham Park

18103-6218

Local Institution - 0180, Allentown

29572-4607

Local Institution - 0115, Myrtle Beach

77024-2843

Local Institution - 0284, Houston

77030-3721

Local Institution - 0195, Houston

B7602CBM

Local Institution - 0129, Mar del Plata

B2700

Local Institution - 0061, Pergamino

C1012

Local Institution - 0185, Buenos Aires

F5300COE

Local Institution - 0369, La Rioja

J5402DIL

Local Institution - 0394, San Juan

80530-010

Local Institution - 0100, Curitiba

59075-740

Local Institution - 0321, Natal

98700-000

Local Institution - 0058, Ijuí

90035-001

Local Institution - 0063, Porto Alegre

90035-903

Local Institution - 0056, Porto Alegre

90110-270

Local Institution - 0057, Porto Alegre

13083 970

Local Institution - 0086, Campinas

09060-650

Local Institution - 0059, Santo André

15090-000

Local Institution - 0096, São José do Rio Preto

22250-905

Local Institution - 0189, Rio de Janeiro

22793-080

Local Institution - 0060, Rio de Janeiro

01321-001

Local Institution - 0080, São Paulo

01327-0001

Local Institution - 0273, São Paulo

05652- 900

Local Institution - 0328, São Paulo

L6R 3J7

Local Institution - 0151, Brampton

M2K 1E1

Local Institution - 0191, Toronto

H2X 0A9

Local Institution - 0143, Montreal

071000

Local Institution - 0320, Baoding Shi

656 53

Local Institution - 0108, Brno

656 91

Local Institution - 0093, Brno

779 00

Local Institution - 0049, Olomouc

140 59

Local Institution - 0050, Prague

180 81

Local Institution - 0361, Prague

06189

Local Institution - 0384, Nice

35042 Rennes

Local Institution - 0380, Rennes

01307

Local Institution - 0090, Dresden

NT

Local Institution - 0045, Hong Kong

Unknown

Local Institution - 0146, Hong Kong

00128

Local Institution - 0046, Rome

00152

Local Institution - 0385, Rome

010-8543

Local Institution - 0340, Akita

036-8563

Local Institution - 0358, Hirosaki-shi

260-8717

Local Institution - 0346, Chiba

285-8741

Local Institution - 0339, Sakura-Shi

791-0280

Local Institution - 0307, Matsuyama

0608543

Local Institution - 0281, Sapporo

860-0008

Local Institution - 0324, Kumamoto

602-8566

Local Institution - 0342, Kamigyō-ku

431-3192

Local Institution - 0309, Hamamatsu

951-8520

Local Institution - 0327, Niigata

565-0871

Local Institution - 0338, Osaka

641-8510

Local Institution - 0278, Wakayama

85-796

Local Institution - 0383, Bydgoszcz

75-581

Local Institution - 0136, Koszalin

93-513

Local Institution - 0009, Lodz

20-090

Local Institution - 0013, Lublin

60-848

Local Institution - 0065, Poznan

02 797

Local Institution, Warsaw

04-073

Local Institution - 0095, Warsaw

00935

Local Institution - 0329, Rio Piedras

00927

Local Institution - 0359, San Juan

022328

Local Institution - 0042, Bucharest

405-760

Local Institution - 0298, Incheon

02841

Local Institution - 0370, Seoul

03080

Local Institution - 0171, Seoul

05505

Local Institution - 0193, Seoul

06351

Local Institution - 0187, Seoul

08916

Local Institution - 0073, Barcelona

08208

Local Institution - 0124, Sabadell (Barcelona)

01330

Local Institution - 0094, Adana

06620

Local Institution - 0119, Ankara

SW3 6JJ

Local Institution - 0173, London

M20 4BX

Local Institution - 0098, Manchester

HA6 2RN

Local Institution - 0008, Northwood

NG5 1PB

Local Institution - 0051, Nottingham

OX4 6LB

Local Institution - 0265, Oxford

GU2 7XX

Local Institution - 0048, Guildford

NW1 2PG

Local Institution - 0154, London

Sponsors
All Listed Sponsors
lead

Bristol-Myers Squibb

INDUSTRY