Effects of Platelet Concentrates on Palatal Wound Healing

NACompletedINTERVENTIONAL
Enrollment

36

Participants

Timeline

Start Date

May 1, 2018

Primary Completion Date

February 10, 2019

Study Completion Date

June 10, 2019

Conditions
Wound HealPlatelets; DefectPeriodontal InflammationGingival Recession
Interventions
BIOLOGICAL

AFG application on palatinal wound healing

9 ml venous blood collected from the patient was transferred to the tube without any anticoagulants. In the protocol, venous blood collected in the tube was centrifuged for 2 minutes at 2700 rpm (approximately 692 g) in a special centrifuge (Medifuge, Silfradent, Italy) to obtain two layers: the lower layer of red blood cells and the upper layer of AFG. The AFG at the top of the tube was collected by means of an injector and transferred to the metal godet. It was held for 15-20 minutes for polymerization. After polymerization occurred, the polymerized AFG in the metal gum was applied to the wound surface in the donor site . No suture or tissue glue was used. Adhesive properties of AFG were utilized.

BIOLOGICAL

i-PRF application on palatinal wound healing

10 ml venous blood collected from the patient was transferred to the tube without any anticoagulants. Based on G force, collected venous blood were centrifuged at 2300 rpm (about 241 g) in a centrifuge (PC-O2, Process for PRF, Nice, France) for 3 minutes to obtain two layers: The two layers are the lower layer of red blood cells and the upper layer of i-PRF. The i-PRF at the top of the tube was collected with a syringe and transferred to the metal godet. It was held for 20-25 minutes for polymerization. After the polymerization, the polymerized i-PRF was applied to the wound surface in the donor site. No suture or tissue glue was used. Adhesive properties of AFG were utilized.

OTHER

control

no application

Trial Locations (1)

44280

Inonu University, Faculty of Dentistry, Department of Periodontics,, Malatya

All Listed Sponsors
lead

Inonu University

OTHER

NCT04097509 - Effects of Platelet Concentrates on Palatal Wound Healing | Biotech Hunter | Biotech Hunter