Improving Pain Control in Paraesophageal Hernia Repair: Intravenous Lidocaine Versus Placebo

PHASE4RecruitingINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

June 21, 2018

Primary Completion Date

January 31, 2026

Study Completion Date

January 31, 2026

Conditions
Hernia, Paraesophageal
Interventions
DRUG

IV lidocaine

Patients randomized to the IV lidocaine group will receive a 100 mg lidocaine bolus on induction then an infusion of 1.5 mg/kg/hr prior to incision. This infusion will continue throughout operation and into the PACU for 1 hour OR until the 2gm/250 mL D5W bag has been infused, whichever occurs first.

DRUG

Placebo

o Patients randomized to the placebo group will receive D5W solution (as this is the carrier for lidocaine) at the same volume and rate as the IV lidocaine.

Trial Locations (1)

28203

RECRUITING

Atrium Health - Carolinas Medical Center, Charlotte

All Listed Sponsors
lead

Wake Forest University Health Sciences

OTHER