NCT04093219View on ClinicalTrials.gov

PANDORA: Delirium Prevention After Cardiac Surgery Using IV Acetaminophen to Prevent Postoperative Delirium in Older Cardiac Surgical Patients

PHASE3Active, not recruitingINTERVENTIONAL
Enrollment

900

Participants

Timeline

Start Date

August 11, 2020

Primary Completion Date

March 4, 2025

Study Completion Date

March 31, 2026

Conditions
Delirium in Old AgeDeliriumCoronary Artery Disease
Interventions
DRUG

IV acetaminophen

use of IV tylenol for pain

OTHER

Placebo

Volume of the placebo (saline) will match that of IV acetaminophen at 100ml 0.9% NaCl

Trial Locations (10)

10032

Columbia University Irving Medical Center, New York

10467

Albert Einstein College of Medicine- Montefiore, The Bronx

15213

University of Pittsburgh Medical Center, Pittsburgh

35233

University of Alabama at Birmingham, Birmingham

90095

University of California Los Angeles, Los Angeles

92697

University of California Irvine, Irvine

06510

Yale University/Yale New Haven Hospital, New Haven

02114

Massachusetts General Hospital, Boston

02115

Brigham and Women's Hospital, Boston

02215

Beth Israel Deaconess Medical Center, Boston

All Listed Sponsors
collaborator

National Institute on Aging (NIA)

NIH

lead

Beth Israel Deaconess Medical Center

OTHER