VNS-induced Corticospinal Plasticity

NACompletedINTERVENTIONAL
Enrollment

26

Participants

Timeline

Start Date

September 22, 2019

Primary Completion Date

November 9, 2021

Study Completion Date

November 9, 2021

Conditions
Stroke
Interventions
OTHER

Paired-Associative Stimulation (PAS)

Simultaneous activation of connections in motor cortex via stimulation to the nerves and brain.

OTHER

Vagus Nerve Stimulation (VNS)

Recruits the auricular branch of the vagus nerve which activates brain structures that release chemicals mediating cortical plasticity.

OTHER

Sham Stimulation

Sub-threshold stimulation that does not activate neural structures.

Trial Locations (1)

15213

University of Pittsburgh, Pittsburgh

All Listed Sponsors
lead

University of Pittsburgh

OTHER

NCT04088565 - VNS-induced Corticospinal Plasticity | Biotech Hunter | Biotech Hunter