Toripalimab in Combination With Nab-Paclitaxel For Patients With Metastatic or Recurrent Triple-Negative Breast Cancer (TNBC) With or Without Systemic Treatment

PHASE3Active, not recruitingINTERVENTIONAL
Enrollment

531

Participants

Timeline

Start Date

December 21, 2018

Primary Completion Date

February 28, 2025

Study Completion Date

December 31, 2025

Conditions
Triple-Negative Breast Cancer
Interventions
DRUG

JS001

JS001 240mg, i.v., q3w; Other name: Toripalimab

DRUG

Nab-Paclitaxel

Nab-Paclitaxel 125 mg/m2, i.v., d1, d8, q3w

DRUG

Placebo

Placebo, i.v., q3w;

DRUG

Nab-Paclitaxel

Nab-Paclitaxel 125 mg/m2, i.v., d1, d8, q3w

Trial Locations (53)

100071

The Fifth Medical Center of PLA General Hospital, Beijing

Unknown

Beijing Hospital, Beijing

Chinese PLA General Hospital, Beijing

Peking University Shougang Hospital, Beijing

Affiliated Hospital of Hebei University, Baoding

The first affiliated Hospital of Bengbu Medical College, Bengbu

Jilin Cancer Hospital, Changchun

The First Hospital of Jilin University, Changchun

Hunan Cancer Hospital, Changsha

Affiliated Hospital of Chengde Medical University, Chengde

Sichuan Cancer Hospital, Chengdu

Chongqing Cancer Hospital, Chongqing

The Second Hospital of Dalian Medical University, Dalian

The First People's Hospital of Foshan, Foshan

Fujian Medical University Union Hospital, Fuzhou

Guangdong General Hospital, Guangzhou

Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou

Sun Yat-sen University Cancer Center, Guangzhou

The First Affiliated Hospital, Sun Yat-sen University, Guangzhou

The Women and Children's Hospital of Guangdong Province, Guangzhou

The First Affiliated Hospital Zhejiang University, Hangzhou

The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou

Zhejiang Cancer Hospital, Hangzhou

Harbin Medical University Cancer Hospital, Harbin

Anhui Province Hospital & The First Affiliated Hospital of USTC, Hefei

The First Affiliated Hospital of Anhui Medical University, Hefei

The Second Hospital of Anhui Medical University, Hefei

Shandong Cancer Hospital, Jinan

Yunnan Cancer Hospital, Kunming

Linyi Cancer Hospital, Linyi

The Affiliated Hospita of of Southwest Medical University, Luzhou

Jiangxi Cancer Hospital, Nanchang

The Third Hospital of Nanchang, Nanchang

Jiangsu Cancer Hospital, Nanjing

Jiangsu Province Hospital, Nanjing

The Affiliated Hospital of Qingdao University, Qingdao

Changhai Hospital, Shanghai

Shanghai General Hospital, Shanghai

Liaoning Cancer Hospital&Intitute, Shenyang

The First Hospital of China Medical University, Shenyang

The Fourth Hospital of Hebei Medical University, Shijiazhuang

Cancer Hospital Affiliated to Xinjiang Medical University, Ürümqi

Hubei Cancer Hospital, Wuhan

Tongji Hospital Tongji Medical College Huazhong University of Science and Technology, Wuhan

Union Hospital Tongji Medical College Huazhong University of Science and Technology, Wuhan

Affiliated Hospital of Jiangnan University(Wuxi NO.4 People's Hospital), Wuxi

The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an

The Second Affiliated Hospital of The PLA Air Force Military Medical University, Xi'an

The First Affiliated Hospital of Xiamen University, Xiamen

Xiangyang Central Hospital, Xiangyang

General Hospital of Ningxia Medical University, Yinchuan

Henan Provincial People's Hospital, Zheng'zhou

Henan Cancer Hospital, Zhengzhou

All Listed Sponsors
lead

Shanghai Junshi Bioscience Co., Ltd.

OTHER